cediranib

Ligand id: 5664

Name: cediranib

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 8
Topological polar surface area 72.5
Molecular weight 450.21
XLogP 4
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
4-[(4-fluoro-2-methyl-1H-indol-5-yl)oxy]-6-methoxy-7-[3-(pyrrolidin-1-yl)propoxy]quinazoline
International Nonproprietary Names
INN number INN
8764 cediranib
Synonyms
AZD 2171 | ZD 2171
Database Links
CAS Registry No. 288383-20-0
ChEMBL Ligand CHEMBL491473
PubChem CID 9933475
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Wikipedia Cediranib
Comments
Cediranib is a highly potent VEGFR2 (KDR) inhibitor [2]. This compound was in the AstraZeneca/NCATS repurposing list from 2012.