canertinib

Ligand id: 5675

Name: canertinib

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 7
Hydrogen bond donors 2
Rotatable bonds 10
Topological polar surface area 88.61
Molecular weight 485.16
XLogP 3.04
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
N-{4-[(3-chloro-4-fluorophenyl)amino]-7-[3-(morpholin-4-yl)propoxy]quinazolin-6-yl}prop-2-enamide
International Nonproprietary Names
INN number INN
8256 canertinib
Synonyms
CI 1033 | CI-1033 | PD 183805 dihydrochloride [4]
Database Links
CAS Registry No. 267243-28-7
ChEMBL Ligand CHEMBL31965
PubChem CID 156414
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Wikipedia Canertinib
Comments
Canertinib is an irreversible inhibitor which blocks signal transduction through all four members of the erbB family [1].