CI-1040

Ligand id: 5676

Name: CI-1040

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 2
Hydrogen bond donors 2
Rotatable bonds 7
Topological polar surface area 50.36
Molecular weight 477.98
XLogP 5.49
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
2-[(2-chloro-4-iodophenyl)amino]-N-(cyclopropylmethoxy)-3,4-difluorobenzamide
Synonyms
CI 1040 | CI1040 | PD-184352 | PD184352
Database Links
CAS Registry No. 212631-79-3
ChEMBL Ligand CHEMBL105442
PubChem CID 6918454
Search Google for chemical match using the InChIKey GFMMXOIFOQCCGU-UHFFFAOYSA-N
Search Google for chemicals with the same backbone GFMMXOIFOQCCGU
Search UniChem for chemical match using the InChIKey GFMMXOIFOQCCGU-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone GFMMXOIFOQCCGU
Comments
CI-1040 is an investigational MEK1/2 inhibitor [1], which acts as a negative allosteric modulator of kinase activity.