enzastaurin

Ligand id: 5693

Name: enzastaurin

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 7
Hydrogen bond donors 1
Rotatable bonds 5
Topological polar surface area 72.16
Molecular weight 515.23
XLogP 5.36
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
3-(1-methyl-1H-indol-3-yl)-4-{1-[1-(pyridin-2-ylmethyl)piperidin-4-yl]-1H-indol-3-yl}-2,5-dihydro-1H-pyrrole-2,5-dione
International Nonproprietary Names
INN number INN
8426 enzastaurin
Synonyms
LY-317615 | LY317615
Database Links
CAS Registry No. 170364-57-5
ChEMBL Ligand CHEMBL300138
PubChem CID 176167
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Wikipedia Enzastaurin
Comments
Enzastaurin is a selective inhibitor of protein kinase Cβ [2-3]. Note that reported affinity values may have been generated using the hydrochloride salt (PubChem CID 176166).