AG 490

Ligand id: 5916

Name: AG 490

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 3
Rotatable bonds 5
Topological polar surface area 93.35
Molecular weight 294.1
XLogP 3.48
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
(2E)-N-benzyl-2-cyano-3-(3,4-dihydroxyphenyl)prop-2-enamide
Synonyms
AG-490 | tyrphostin AG490 | tyrphostin B42
Database Links
CAS Registry No. 133550-30-8
ChEMBL Ligand CHEMBL56543
GtoPdb PubChem SID 178102539
PubChem CID 5328779
Search Google for chemical match using the InChIKey TUCIOBMMDDOEMM-RIYZIHGNSA-N
Search Google for chemicals with the same backbone TUCIOBMMDDOEMM
Search UniChem for chemical match using the InChIKey TUCIOBMMDDOEMM-RIYZIHGNSA-N
Search UniChem for chemicals with the same backbone TUCIOBMMDDOEMM
Comments
Tyrphostin AG 490 is an inhibitor of the epidermal growth factor receptor (EGFR) tyrosine kinase. Its discovery is reported in [3] where it is compound 44(-)..