tranilast

Ligand id: 6326

Name: tranilast

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 7
Topological polar surface area 84.86
Molecular weight 327.11
XLogP 3.75
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes
IUPAC Name
2-[3-(3,4-dimethoxyphenyl)prop-2-enoylamino]benzoic acid
International Nonproprietary Names
INN number INN
5070 tranilast
Synonyms
MK-341 | SB-252218
Database Links
CAS Registry No. 53902-12-8 (source: SciFinder)
ChEMBL Ligand CHEMBL415324
GtoPdb PubChem SID 178102944
PubChem CID 5282230
RCSB PDB Ligand D27
Search Google for chemical match using the InChIKey NZHGWWWHIYHZNX-CSKARUKUSA-N
Search Google for chemicals with the same backbone NZHGWWWHIYHZNX
Search PubMed clinical trials tranilast
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Search UniChem for chemical match using the InChIKey NZHGWWWHIYHZNX-CSKARUKUSA-N
Search UniChem for chemicals with the same backbone NZHGWWWHIYHZNX
Wikipedia Tranilast
Comments
Tranilast is an anti-allergic drug, with a complex mechanism of action [1,3], and potential antiproliferative activity [2].