imidapril

Ligand id: 6377

Name: imidapril

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 9
Hydrogen bond donors 2
Rotatable bonds 11
Topological polar surface area 116.25
Molecular weight 405.19
XLogP 3.08
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes
Is prodrug? Yes
Active form imidaprilat
IUPAC Name
(4S)-3-[(2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoyl]-1-methyl-2-oxoimidazolidine-4-carboxylic acid
International Nonproprietary Names
INN number INN
6394 imidapril
Synonyms
imidapril hydrochloride
Database Links
CAS Registry No. 89371-37-9 (source: PubChem)
ChEMBL Ligand CHEMBL317094
PubChem CID 5464343
Search Google for chemical match using the InChIKey KLZWOWYOHUKJIG-BPUTZDHNSA-N
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Search UniChem for chemical match using the InChIKey KLZWOWYOHUKJIG-BPUTZDHNSA-N
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Wikipedia Imidapril
Comments
Imidapril is an ACE inhibitor, administered as a prodrug which is then metabolised to the active form, imidaprilat.