zofenopril

Ligand id: 6462

Name: zofenopril

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 9
Topological polar surface area 125.28
Molecular weight 429.11
XLogP 5.75
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes
Is prodrug? Yes
Active form zofenoprilat
IUPAC Name
(2S,4S)-1-[(2S)-3-(benzoylsulfanyl)-2-methylpropanoyl]-4-phenylsulfanylpyrrolidine-2-carboxylic acid
International Nonproprietary Names
INN number INN
5535 zofenopril
Synonyms
SO-26991 | SQ-26900
Database Links
CAS Registry No. 81872-10-8 (source: PubChem)
ChEMBL Ligand CHEMBL331378
GtoPdb PubChem SID 178103076
PubChem CID 92400
Search Google for chemical match using the InChIKey IAIDUHCBNLFXEF-MNEFBYGVSA-N
Search Google for chemicals with the same backbone IAIDUHCBNLFXEF
Search PubMed clinical trials zofenopril
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Search UniChem for chemical match using the InChIKey IAIDUHCBNLFXEF-MNEFBYGVSA-N
Search UniChem for chemicals with the same backbone IAIDUHCBNLFXEF
Wikipedia Zofenopril
Comments
Metabolised to the active from zofenoprilat. The United States Adopted Name (USAN) for this compound is zofenopril calcium (PubChem CID 3033690).