daglutril

Ligand id: 6506

Name: daglutril

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 8
Hydrogen bond donors 2
Rotatable bonds 13
Topological polar surface area 113.01
Molecular weight 534.27
XLogP 7.78
No. Lipinski's rules broken 2

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Is prodrug? Yes
Active form KC-12615
IUPAC Name
2-[(3S)-3-[[1-[(2R)-2-ethoxycarbonyl-4-phenylbutyl]cyclopentanecarbonyl]amino]-2-oxo-4,5-dihydro-3H-1-benzazepin-1-yl]acetic acid
International Nonproprietary Names
INN number INN
8351 daglutril
Synonyms
SLV 306 | SLV-306 | SLV306
Database Links
CAS Registry No. 182821-27-8 (source: PubChem)
DrugBank Ligand DB05796
GtoPdb PubChem SID 178103120
PubChem CID 3038505
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Search UniChem for chemical match using the InChIKey XMQODGUTLZXUGZ-RPBOFIJWSA-N
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Comments
This compound is a prodrug for a dual endothelin converting enzyme/neutral endopeptidase inhibitor.