spiraprilat

Ligand id: 6576

Name: spiraprilat

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 7
Hydrogen bond donors 3
Rotatable bonds 9
Topological polar surface area 157.54
Molecular weight 438.13
XLogP 4.26
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes (FDA (1994))
Prodrug spirapril
IUPAC Name
(7S)-8-[(2S)-2-[[(2S)-1-hydroxy-1-oxo-4-phenylbutan-2-yl]amino]propanoyl]-1,4-dithia-8-azaspiro[4.4]nonane-7-carboxylic acid
International Nonproprietary Names
INN number INN
6357 spiraprilat
Synonyms
SCH-33861
Database Links
CAS Registry No. 83602-05-5 (source: PubChem)
ChEMBL Ligand CHEMBL579
PubChem CID 3033702
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Wikipedia Spiraprilat
Comments
ACE inhibitor drug metobolically generated from spirapril prodrug