tirofiban

Ligand id: 6586

Name: tirofiban

IUPHAR Pharmacology Education Project (PEP) logo

View more information in the IUPHAR Pharmacology Education Project: tirofiban

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 3
Rotatable bonds 14
Topological polar surface area 113.11
Molecular weight 440.23
XLogP 4.01
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes (FDA (1998))
IUPAC Name
(2S)-2-(butylsulfonylamino)-3-[4-(4-piperidin-4-ylbutoxy)phenyl]propanoic acid
International Nonproprietary Names
INN number INN
7345 tirofiban
Synonyms
Aggrastat® | L-700462 | MK-383 | tirofiban hydrochloride (monohydrate)
Database Links
CAS Registry No. 144494-65-5
ChEMBL Ligand CHEMBL916
DrugBank Ligand DB00775
PubChem CID 60947
RCSB PDB Ligand AGG
Search Google for chemical match using the InChIKey COKMIXFXJJXBQG-NRFANRHFSA-N
Search Google for chemicals with the same backbone COKMIXFXJJXBQG
Search PubMed clinical trials tirofiban
Search PubMed titles tirofiban
Search PubMed titles/abstracts tirofiban
Search UniChem for chemical match using the InChIKey COKMIXFXJJXBQG-NRFANRHFSA-N
Search UniChem for chemicals with the same backbone COKMIXFXJJXBQG
Wikipedia Tirofiban
Comments
Tirofiban is a rapidly-active but short-acting glycoprotein IIb/IIIa inhibitor type antiplatelet drug.