CCG-977

Ligand id: 6762

Name: CCG-977

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 8
Topological polar surface area 83.65
Molecular weight 522.02
XLogP 7.29
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
N-[4-[[3,5-bis(trifluoromethyl)phenyl]sulfamoyl]phenyl]-4-chlorobenzamide
Synonyms
CCG 977 | CCG977
Database Links
PubChem CID 2725689
Search Google for chemical match using the InChIKey VBZKJHSBGYDJAN-UHFFFAOYSA-N
Search Google for chemicals with the same backbone VBZKJHSBGYDJAN
Search UniChem for chemical match using the InChIKey VBZKJHSBGYDJAN-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone VBZKJHSBGYDJAN
Comments
CCG-977 is an analogue of CCG 1423, both of which inhibit RhoA transcriptional signaling via an unkown mechanism of action. Both are tool compounds for disrupting the transcriptional responses of the Rho pathway in cancer.