acetazolamide

Ligand id: 6792

Name: acetazolamide

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Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 7
Hydrogen bond donors 2
Rotatable bonds 3
Topological polar surface area 151.66
Molecular weight 221.99
XLogP -1.53
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes (FDA (1995))
IUPAC Name
N-(5-sulfamoyl-1,3,4-thiadiazol-2-yl)acetamide
International Nonproprietary Names
INN number INN
481 acetazolamide
Synonyms
Diamox®
Database Links
CAS Registry No. 59-66-5
ChEMBL Ligand CHEMBL20
DrugBank Ligand DB00819
PubChem CID 1986
RCSB PDB Ligand AZM
Search Google for chemical match using the InChIKey BZKPWHYZMXOIDC-UHFFFAOYSA-N
Search Google for chemicals with the same backbone BZKPWHYZMXOIDC
Search PubMed clinical trials acetazolamide
Search PubMed titles acetazolamide
Search PubMed titles/abstracts acetazolamide
Search UniChem for chemical match using the InChIKey BZKPWHYZMXOIDC-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone BZKPWHYZMXOIDC
SynPHARM 78858 (in complex with carbonic anhydrase 1)
79183 (in complex with carbonic anhydrase 12)
78867 (in complex with carbonic anhydrase 14)
79197 (in complex with carbonic anhydrase 7)
Wikipedia Acetazolamide
Comments
Carbonic anhydrase inhibitor