enzalutamide

Ligand id: 6812

Name: enzalutamide

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Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 1
Rotatable bonds 5
Topological polar surface area 108.53
Molecular weight 464.09
XLogP 4.77
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes (FDA (2012), EMA (2013))
IUPAC Name
4-{3-[4-cyano-3-(trifluoromethyl)phenyl]-5,5-dimethyl-4-oxo-2-sulfanylideneimidazolidin-1-yl}-2-fluoro-N-methylbenzamide
International Nonproprietary Names
INN number INN
9621 enzalutamide
Synonyms
MDV-3100 | MDV3100 | Xtandi®
Database Links
CAS Registry No. 915087-33-1
ChEMBL Ligand CHEMBL1082407
DrugBank Ligand DB08899
PubChem CID 15951529
Search Google for chemical match using the InChIKey WXCXUHSOUPDCQV-UHFFFAOYSA-N
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Search UniChem for chemical match using the InChIKey WXCXUHSOUPDCQV-UHFFFAOYSA-N
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Wikipedia Enzalutamide
Comments
Enzalutamide is an androgen receptor antagonist