hydroxyurea

Ligand id: 6822

Name: hydroxyurea

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 2
Hydrogen bond donors 3
Rotatable bonds 1
Topological polar surface area 75.35
Molecular weight 76.03
XLogP -1.61
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes (FDA (1998))
IUPAC Name
hydroxyurea
Synonyms
Droxia® | Hydrea® | hydroxycarbamide | SQ-1089
Database Links
CAS Registry No. 127-07-1
ChEMBL Ligand CHEMBL467
DrugBank Ligand DB01005
PubChem CID 3657
RCSB PDB Ligand NHY
Search Google for chemical match using the InChIKey VSNHCAURESNICA-UHFFFAOYSA-N
Search Google for chemicals with the same backbone VSNHCAURESNICA
Search UniChem for chemical match using the InChIKey VSNHCAURESNICA-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone VSNHCAURESNICA
Wikipedia Hydroxyurea
Comments
Inhibits ribonucleoside-diphosphate reductase (RR1).