nateglinide

Ligand id: 6833

Name: nateglinide

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 7
Topological polar surface area 66.4
Molecular weight 317.2
XLogP 6.38
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes (FDA (2000), EMA (2001))
IUPAC Name
(2R)-3-phenyl-2-{[(1r,4r)-4-(propan-2-yl)cyclohexyl]formamido}propanoic acid
International Nonproprietary Names
INN number INN
7594 nateglinide
Synonyms
AY-4166 | SDZ-DJN-608 | Starlix®
Database Links
CAS Registry No. 105816-04-4
ChEMBL Ligand CHEMBL783
DrugBank Ligand DB00731
PubChem CID 5311309
Search Google for chemical match using the InChIKey OELFLUMRDSZNSF-BRWVUGGUSA-N
Search Google for chemicals with the same backbone OELFLUMRDSZNSF
Search PubMed clinical trials nateglinide
Search PubMed titles nateglinide
Search PubMed titles/abstracts nateglinide
Search UniChem for chemical match using the InChIKey OELFLUMRDSZNSF-BRWVUGGUSA-N
Search UniChem for chemicals with the same backbone OELFLUMRDSZNSF
Wikipedia Nateglinide
Comments
A sulfonylurea receptor 1, Kir6.2 blocker, but belonging to the metiglinides drug family. Note that the PubChem CID listed here is a slightly different isomer to the ChEMBL ligand and the INN structure.