pegaptanib

Ligand id: 6836

Name: pegaptanib

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 13
Hydrogen bond donors 4
Rotatable bonds 27
Topological polar surface area 180.56
Molecular weight 541.28
XLogP 0.58
No. Lipinski's rules broken 2

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes (FDA (2004), EMA (2006))
IUPAC Name
7-[[(2S)-2,6-bis(2-methoxyethoxycarbonylamino)hexanoyl]amino]heptoxy-methylphosphinic acid
International Nonproprietary Names
INN number INN
8215 pegaptanib
Synonyms
EYEOO1 | Macugen® | NX183 | pegaptanib sodium
Database Links
CAS Registry No. 222716-86-1
DrugBank Ligand DB04895
GtoPdb PubChem SID 178103442
PubChem CID 56603655
Search Google for chemical match using the InChIKey WLCZTRVUXYALDD-IBGZPJMESA-N
Search Google for chemicals with the same backbone WLCZTRVUXYALDD
Search PubMed clinical trials pegaptanib
Search PubMed titles pegaptanib
Search PubMed titles/abstracts pegaptanib
Search UniChem for chemical match using the InChIKey WLCZTRVUXYALDD-IBGZPJMESA-N
Search UniChem for chemicals with the same backbone WLCZTRVUXYALDD
Wikipedia Pegaptanib
Comments
Note that the PubChem CID listed here represents only the backbone of the molecule and does not include the nucleic acid aptamer attached to the phosphate group. Acts as a vascular endothelial growth factor A antagonist.