repaglinide

Ligand id: 6841

Name: repaglinide

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 11
Topological polar surface area 78.87
Molecular weight 452.27
XLogP 6.09
No. Lipinski's rules broken 2

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes (FDA (1997), EMA (1998))
IUPAC Name
2-ethoxy-4-[2-[[(1S)-3-methyl-1-(2-piperidin-1-ylphenyl)butyl]amino]-2-oxoethyl]benzoic acid
International Nonproprietary Names
INN number INN
6818 repaglinide
Synonyms
(-)-repaglinide | AGEE-623ZW | Prandin®
Database Links
CAS Registry No. 135062-02-1 (source: Scifinder)
ChEMBL Ligand CHEMBL1272
DrugBank Ligand DB00912
PubChem CID 65981
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Search UniChem for chemical match using the InChIKey FAEKWTJYAYMJKF-QHCPKHFHSA-N
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Wikipedia Repaglinide
Comments
A sulfonylurea receptor 1, Kir6.2 blocker, belonging to the metiglinides drug family.