ribavirin

Ligand id: 6842

Name: ribavirin

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 9
Hydrogen bond donors 4
Rotatable bonds 3
Topological polar surface area 143.72
Molecular weight 244.08
XLogP -3.04
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes (FDA (1985), EMA (1999))
IUPAC Name
1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2,4-triazole-3-carboxamide
International Nonproprietary Names
INN number INN
3543 ribavirin
Synonyms
Copegus® | ribofluranosyl carboxamide | Virazole®
Database Links
CAS Registry No. 36791-04-5
ChEBI CHEBI:63580
ChEMBL Ligand CHEMBL1643
DrugBank Ligand DB00811
GtoPdb PubChem SID 178103448
PubChem CID 37542
RCSB PDB Ligand RBV
Search Google for chemical match using the InChIKey IWUCXVSUMQZMFG-AFCXAGJDSA-N
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Wikipedia Ribavirin
Comments
Inhibits inosine-5'-monophosphate dehydrogenase 1 and RNA and also inhibits hepatitis C virus RNA-dependent RNA polymerase (NS5B).