trilostane

Ligand id: 6850

Name: trilostane

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 0
Topological polar surface area 76.78
Molecular weight 329.2
XLogP 2.64
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes (FDA (date of approval not specified))
Withdrawn drug? Yes
International Nonproprietary Names
INN number INN
3928 trilostane
Synonyms
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Database Links
CAS Registry No. 13647-35-3
ChEMBL Ligand CHEMBL1200907
DrugBank Ligand DB01108
PubChem CID 656583
Search Google for chemical match using the InChIKey KVJXBPDAXMEYOA-CXANFOAXSA-N
Search Google for chemicals with the same backbone KVJXBPDAXMEYOA
Search PubMed clinical trials trilostane
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Search UniChem for chemical match using the InChIKey KVJXBPDAXMEYOA-CXANFOAXSA-N
Search UniChem for chemicals with the same backbone KVJXBPDAXMEYOA
Wikipedia Trilostane
Comments
Trilostane is a 3 β-hydroxysteroid dehydrogenase (gene symbol HSD3B1) inhibitor. It is now used mainly in veterinary practice.