encenicline

Ligand id: 6926

Name: encenicline

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 3
Topological polar surface area 60.58
Molecular weight 320.08
XLogP 2.69
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
N-[(3R)-1-azabicyclo[2.2.2]octan-3-yl]-7-chloro-1-benzothiophene-2-carboxamide
International Nonproprietary Names
INN number INN
9775 encenicline
Synonyms
EVP 6124 | EVP-6124 | EVP6124
Database Links
CAS Registry No. 550999-75-2 (source: Scifinder)
ChEMBL Ligand CHEMBL2151572
PubChem CID 46196517
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Search UniChem for chemical match using the InChIKey SSRDSYXGYPJKRR-ZDUSSCGKSA-N
Search UniChem for chemicals with the same backbone SSRDSYXGYPJKRR
Wikipedia Encenicline
Comments
This compound was developed as part of EnVivo Pharmaceuticals alpha-7 agonist program [3]. The compound exhibits good brain penetration and an adequate exposure time for clinical utility [3].
EnVivo changed its name to FORUM Pharmaceuticals Inc. in April 2014.