AZD3839

Ligand id: 6931

Name: AZD3839

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 4
Topological polar surface area 76.72
Molecular weight 433.15
XLogP 5.16
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
(3S)-3-[2-(difluoromethyl)pyridin-4-yl]-7-fluoro-3-[3-(pyrimidin-5-yl)phenyl]-2,3-dihydro-1H-isoindol-1-amine
Synonyms
AZD 3839 | AZD-3839
Database Links
CAS Registry No. 1227163-84-9 (source: Scifinder)
PubChem CID 60210951
Search Google for chemical match using the InChIKey QXKYWSDUVAJHNZ-CGAIIQECSA-N
Search Google for chemicals with the same backbone QXKYWSDUVAJHNZ
Search UniChem for chemical match using the InChIKey QXKYWSDUVAJHNZ-CGAIIQECSA-N
Search UniChem for chemicals with the same backbone QXKYWSDUVAJHNZ
Comments
AstraZeneca BACE1 inhibitor AZD3839 recently progressed into Phase 1 clinical trials for Alzheimer's Disease.