dextromethorphan

Ligand id: 6953

Name: dextromethorphan

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View more information in the IUPHAR Pharmacology Education Project: dextromethorphan

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 1
Hydrogen bond donors 0
Rotatable bonds 1
Topological polar surface area 12.47
Molecular weight 271.19
XLogP 4.21
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes (FDA (no history prior to 1982))
International Nonproprietary Names
INN number INN
166 dextromethorphan
Synonyms
d-methorphan
Database Links
CAS Registry No. 125-71-3
ChEMBL Ligand CHEMBL52440
DrugBank Ligand DB00514
PubChem CID 5360696
Search Google for chemical match using the InChIKey MKXZASYAUGDDCJ-NJAFHUGGSA-N
Search Google for chemicals with the same backbone MKXZASYAUGDDCJ
Search PubMed clinical trials dextromethorphan
Search PubMed titles dextromethorphan
Search PubMed titles/abstracts dextromethorphan
Search UniChem for chemical match using the InChIKey MKXZASYAUGDDCJ-NJAFHUGGSA-N
Search UniChem for chemicals with the same backbone MKXZASYAUGDDCJ
Wikipedia Dextromethorphan
Comments
Dextromethorphan is a morphinan class sedative. It is available over-the-counter (OTC) for use as an antitussive. At doses much higher than medically recommended, dextromethorphan is used recreationally for its dissociative anesthetic and euphoria producing effects.