pentoxifylline

Ligand id: 7095

Name: pentoxifylline

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Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 7
Hydrogen bond donors 0
Rotatable bonds 5
Topological polar surface area 75.51
Molecular weight 278.14
XLogP -0.1
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Metabolite or derivative
Approved drug? Yes (FDA (1984))
Is prodrug? Yes
Active form lisofylline
IUPAC Name
3,7-dimethyl-1-(5-oxohexyl)-2,3,6,7-tetrahydro-1H-purine-2,6-dione
International Nonproprietary Names
INN number INN
3309 pentoxifylline
Synonyms
BL-191 | Trental®
Database Links
CAS Registry No. 6493-05-6
ChEMBL Ligand CHEMBL628
DrugBank Ligand DB00806
PubChem CID 4740
RCSB PDB Ligand PNX
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Wikipedia Pentoxifylline
Comments
Pentoxifylline is a methylated xanthine derivative drug which acts as a competitive non-selective phosphodiesterase (PDE) inhibitor [1].