alfuzosin

Ligand id: 7109

Name: alfuzosin

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Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 7
Hydrogen bond donors 3
Rotatable bonds 8
Topological polar surface area 99.4
Molecular weight 389.21
XLogP 1.6
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes (FDA (2003))
IUPAC Name
N-{3-[(4-imino-6,7-dimethoxy-3,4-dihydroquinazolin-2-yl)(methyl)amino]propyl}oxolane-2-carboximidic acid
International Nonproprietary Names
INN number INN
5357 alfuzosin
Synonyms
SL-77499-10 | SL-7749910 | Uroxatral®
Database Links
CAS Registry No. 81403-80-7
ChEMBL Ligand CHEMBL709
DrugBank Ligand DB00346
PubChem CID 2092
Search Google for chemical match using the InChIKey WNMJYKCGWZFFKR-UHFFFAOYSA-N
Search Google for chemicals with the same backbone WNMJYKCGWZFFKR
Search PubMed clinical trials alfuzosin
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Search UniChem for chemical match using the InChIKey WNMJYKCGWZFFKR-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone WNMJYKCGWZFFKR
Wikipedia Alfuzosin
Comments
Alfuzosin is an α1-adrenergic receptor antagonist.