atomoxetine

Ligand id: 7118

Name: atomoxetine

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 1
Hydrogen bond donors 1
Rotatable bonds 6
Topological polar surface area 21.26
Molecular weight 255.16
XLogP 5.59
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes (FDA (2002))
IUPAC Name
methyl[(3R)-3-(2-methylphenoxy)-3-phenylpropyl]amine
International Nonproprietary Names
INN number INN
5354 atomoxetine
Synonyms
LY-139603 | Strattera®
Database Links
CAS Registry No. 83015-26-3
ChEMBL Ligand CHEMBL641
DrugBank Ligand DB00289
PubChem CID 54841
Search Google for chemical match using the InChIKey VHGCDTVCOLNTBX-QGZVFWFLSA-N
Search Google for chemicals with the same backbone VHGCDTVCOLNTBX
Search PubMed clinical trials atomoxetine
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Search UniChem for chemical match using the InChIKey VHGCDTVCOLNTBX-QGZVFWFLSA-N
Search UniChem for chemicals with the same backbone VHGCDTVCOLNTBX
Wikipedia Atomoxetine
Comments
Atomoxetine is primarily a norepinephrine (noradrenaline) reuptake inhibitor (NRI), with weak inhibitory effects on SERT (serotonin reuptake), and DAT (dopamine reuptake).