cyclobenzaprine

Ligand id: 7152

Name: cyclobenzaprine

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Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 1
Hydrogen bond donors 0
Rotatable bonds 3
Topological polar surface area 3.24
Molecular weight 275.17
XLogP 8.49
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes (FDA (1977))
IUPAC Name
3-(dibenzo[1,2-a:1',2'-e][7]annulen-11-ylidene)-N,N-dimethylpropan-1-amine
International Nonproprietary Names
INN number INN
791 cyclobenzaprine
Synonyms
Amrix® | Fexmid | MK-130
Database Links
CAS Registry No. 303-53-7
ChEMBL Ligand CHEMBL669
DrugBank Ligand DB00924
PubChem CID 2895
Search Google for chemical match using the InChIKey JURKNVYFZMSNLP-UHFFFAOYSA-N
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Search PubMed clinical trials cyclobenzaprine
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Search UniChem for chemical match using the InChIKey JURKNVYFZMSNLP-UHFFFAOYSA-N
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Wikipedia Cyclobenzaprine
Comments
Cyclobenzaprine is a tricyclic antidepressant similar to amitriptyline. It acts as a skeletal muscle relaxant and central nervous system (CNS) depressant.