methixene

Ligand id: 7232

Name: methixene

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 1
Hydrogen bond donors 0
Rotatable bonds 2
Topological polar surface area 28.54
Molecular weight 309.16
XLogP 5.79
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes
IUPAC Name
1-methyl-3-(9H-thioxanthen-9-ylmethyl)piperidine
International Nonproprietary Names
INN number INN
1739 pimethixene
Synonyms
metixene | SJ-1977 | Trest®
Database Links
ChEMBL Ligand CHEMBL1201342
DrugBank Ligand DB00340
PubChem CID 4167
Search Google for chemical match using the InChIKey MJFJKKXQDNNUJF-UHFFFAOYSA-N
Search Google for chemicals with the same backbone MJFJKKXQDNNUJF
Search PubMed clinical trials pimethixene
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Search UniChem for chemical match using the InChIKey MJFJKKXQDNNUJF-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone MJFJKKXQDNNUJF
Wikipedia Metixine
Comments
Methixene is an antihistamine drug, with anticholinergic activity. There is no information regarding approval for clinical use of this drug on the US FDA website. Other national approval agencies may have granted marketing authorisation.