nebivolol

Ligand id: 7246

Name: nebivolol

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Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 3
Rotatable bonds 6
Topological polar surface area 70.95
Molecular weight 405.18
XLogP 3.15
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes (FDA (2007))
IUPAC Name
1-(6-fluoro-3,4-dihydro-2H-1-benzopyran-2-yl)-2-{[2-(6-fluoro-3,4-dihydro-2H-1-benzopyran-2-yl)-2-hydroxyethyl]amino}ethan-1-ol
International Nonproprietary Names
INN number INN
5969 nebivolol
Synonyms
Bystolic® | R-65824 | Ro-67555
Database Links
CAS Registry No. 99200-09-6
ChEMBL Ligand CHEMBL434394
DrugBank Ligand DB04861
PubChem CID 71301
Search Google for chemical match using the InChIKey KOHIRBRYDXPAMZ-UHFFFAOYSA-N
Search Google for chemicals with the same backbone KOHIRBRYDXPAMZ
Search PubMed clinical trials nebivolol
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Search UniChem for chemical match using the InChIKey KOHIRBRYDXPAMZ-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone KOHIRBRYDXPAMZ
Wikipedia nebivolol
Comments
Nebivolol is a β-blocker, selective for β1-adrenoceptors.
Marketed formulations may contain nebivolol hydrochloride (PubChem CID ).