nefazodone

Ligand id: 7247

Name: nefazodone

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View more information in the IUPHAR Pharmacology Education Project: nefazodone

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 0
Rotatable bonds 10
Topological polar surface area 39.26
Molecular weight 469.22
XLogP 5.03
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes (FDA (1994))
IUPAC Name
1-{3-[4-(3-chlorophenyl)piperazin-1-yl]propyl}-3-ethyl-4-(2-phenoxyethyl)-4,5-dihydro-1H-1,2,4-triazol-5-one
International Nonproprietary Names
INN number INN
5432 nefazodone
Synonyms
BMY-13754 | MJ-13754-1 | Nefadar®
Database Links
CAS Registry No. 83366-66-9
ChEMBL Ligand CHEMBL623
DrugBank Ligand DB01149
GtoPdb PubChem SID 178103821
PubChem CID 4449
Search Google for chemical match using the InChIKey VRBKIVRKKCLPHA-UHFFFAOYSA-N
Search Google for chemicals with the same backbone VRBKIVRKKCLPHA
Search PubMed clinical trials nefazodone
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Search UniChem for chemical match using the InChIKey VRBKIVRKKCLPHA-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone VRBKIVRKKCLPHA
Wikipedia Nefazodone
Comments
Nefazodone is an antidepressant.
Marketed formulations may contain nefazodone hydrochloride (PubChem CID 54911).