protriptyline

Ligand id: 7285

Name: protriptyline

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 1
Hydrogen bond donors 1
Rotatable bonds 4
Topological polar surface area 12.03
Molecular weight 263.17
XLogP 8.59
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes (FDA (1967))
IUPAC Name
3-(11H-dibenzo[1,2-a:1',2'-e][7]annulen-11-yl)-N-methylpropan-1-amine
International Nonproprietary Names
INN number INN
1663 protriptyline
Synonyms
MK-240 | Vivactil®
Database Links
CAS Registry No. 438-60-8
ChEMBL Ligand CHEMBL668
DrugBank Ligand DB00344
GtoPdb PubChem SID 178103859
PubChem CID 4976
Search Google for chemical match using the InChIKey BWPIARFWQZKAIA-UHFFFAOYSA-N
Search Google for chemicals with the same backbone BWPIARFWQZKAIA
Search PubMed clinical trials protriptyline
Search PubMed titles protriptyline
Search PubMed titles/abstracts protriptyline
Search UniChem for chemical match using the InChIKey BWPIARFWQZKAIA-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone BWPIARFWQZKAIA
Wikipedia Protriptyline
Comments
Protriptyline is a tricyclic antidepressant.
Marketed formulations may contain protriptyline hydrochloride (PubChem CID 6603149).