pyrazinamide

Ligand id: 7287

Name: pyrazinamide

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 1
Topological polar surface area 69.86
Molecular weight 123.04
XLogP 0.04
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes (FDA (no history prior to 1971))
IUPAC Name
pyrazine-2-carboximidic acid
International Nonproprietary Names
INN number INN
786 pyrazinamide
Synonyms
Zinamide®
Database Links
CAS Registry No. 98-96-4
ChEMBL Ligand CHEMBL614
DrugBank Ligand DB00339
GtoPdb PubChem SID 178103861
PubChem CID 1046
RCSB PDB Ligand PZA
Search Google for chemical match using the InChIKey IPEHBUMCGVEMRF-UHFFFAOYSA-N
Search Google for chemicals with the same backbone IPEHBUMCGVEMRF
Search PubMed clinical trials pyrazinamide
Search PubMed titles pyrazinamide
Search PubMed titles/abstracts pyrazinamide
Search UniChem for chemical match using the InChIKey IPEHBUMCGVEMRF-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone IPEHBUMCGVEMRF
Wikipedia Pyrazinamide
Comments
This drug is often contained in fixed-mixture formulations with other antibacterial drugs beneficial in the treatment of TB (eg isoniazid and rifampicin).