rabeprazole

Ligand id: 7290

Name: rabeprazole

IUPHAR Pharmacology Education Project (PEP) logo

View more information in the IUPHAR Pharmacology Education Project: rabeprazole

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 8
Topological polar surface area 96.31
Molecular weight 359.13
XLogP 1.49
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes (FDA (1999))
IUPAC Name
2-{[4-(3-methoxypropoxy)-3-methylpyridin-2-yl]methanesulfinyl}-1H-1,3-benzodiazole
International Nonproprietary Names
INN number INN
7112 rabeprazole
Synonyms
AcipHex® | E-3810 | Pariet®
Database Links
CAS Registry No. 17976-89-3
ChEMBL Ligand CHEMBL1219
DrugBank Ligand DB01129
GtoPdb PubChem SID 178103864
PubChem CID 5029
Search Google for chemical match using the InChIKey YREYEVIYCVEVJK-UHFFFAOYSA-N
Search Google for chemicals with the same backbone YREYEVIYCVEVJK
Search PubMed clinical trials rabeprazole
Search PubMed titles rabeprazole
Search PubMed titles/abstracts rabeprazole
Search UniChem for chemical match using the InChIKey YREYEVIYCVEVJK-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone YREYEVIYCVEVJK
Wikipedia Rabeprazole
Comments
Rabeprazole is a proton pump inhibitor. This compound is a prodrug which is converted into the active sulphenamide form in the acid environment of the parietal cells.
Marketed formulations may contain rabeprazole sodium (PubChem CID 14720269).