tadalafil

Ligand id: 7299

Name: tadalafil

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Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 1
Topological polar surface area 74.87
Molecular weight 389.14
XLogP 2.23
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes (EMA (2002), FDA (2003))
International Nonproprietary Names
INN number INN
8136 tadalafil
Synonyms
Adcirca® | Cialis® | IC-351 | IC351
Database Links
CAS Registry No. 171596-29-5
ChEMBL Ligand CHEMBL779
DrugBank Ligand DB00820
PubChem CID 110635
RCSB PDB Ligand CIA
Search Google for chemical match using the InChIKey WOXKDUGGOYFFRN-IIBYNOLFSA-N
Search Google for chemicals with the same backbone WOXKDUGGOYFFRN
Search PubMed clinical trials tadalafil
Search PubMed titles tadalafil
Search PubMed titles/abstracts tadalafil
Search UniChem for chemical match using the InChIKey WOXKDUGGOYFFRN-IIBYNOLFSA-N
Search UniChem for chemicals with the same backbone WOXKDUGGOYFFRN
SynPHARM 79448 (in complex with phosphodiesterase 5A)
Wikipedia Tadalafil
Comments
Tadafil is a phosphodiesterase type 5 (PDE5) inhibitor.