terazosin

Ligand id: 7302

Name: terazosin

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Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 7
Hydrogen bond donors 2
Rotatable bonds 5
Topological polar surface area 87.12
Molecular weight 387.19
XLogP 0.76
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes (FDA (1987))
IUPAC Name
6,7-dimethoxy-2-[4-(oxolane-2-carbonyl)piperazin-1-yl]-3,4-dihydroquinazolin-4-imine
International Nonproprietary Names
INN number INN
4843 terazosin
Synonyms
ABBOTT-45975 | Hytrin®
Database Links
CAS Registry No. 63590-64-7
ChEMBL Ligand CHEMBL611
DrugBank Ligand DB01162
PubChem CID 5401
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Wikipedia Terazosin
Comments
Postsynaptic α1-adrenoceptor inhibitor.
Marketed formulations may contain terazosin hydrochloride (PubChem CID 44383).