thiethylperazine

Ligand id: 7306

Name: thiethylperazine

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 6
Topological polar surface area 60.32
Molecular weight 399.18
XLogP 4.73
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes (FDA (1961))
Withdrawn drug? Yes
IUPAC Name
2-(ethylsulfanyl)-10-[3-(4-methylpiperazin-1-yl)propyl]-10H-phenothiazine
International Nonproprietary Names
INN number INN
1034 thiethylperazine
Synonyms
GS-95 | Torecan®
Database Links
CAS Registry No. 1420-55-9
ChEMBL Ligand CHEMBL1378
DrugBank Ligand DB00372
GtoPdb PubChem SID 178103879
PubChem CID 5440
Search Google for chemical match using the InChIKey XCTYLCDETUVOIP-UHFFFAOYSA-N
Search Google for chemicals with the same backbone XCTYLCDETUVOIP
Search PubMed clinical trials thiethylperazine
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Search UniChem for chemical match using the InChIKey XCTYLCDETUVOIP-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone XCTYLCDETUVOIP
Wikipedia Thiethylperazine
Comments
Thiethylperazine is a phenothiazine class antiemetic. Experiments in a mouse model suggest it may have potential to clear amyloid-β (Aβ) load in Alzheimer's disease [1].