trimipramine

Ligand id: 7317

Name: trimipramine

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Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 2
Hydrogen bond donors 0
Rotatable bonds 4
Topological polar surface area 6.48
Molecular weight 294.21
XLogP 5.54
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes (FDA (1979))
IUPAC Name
3-(5,6-dihydrobenzo[b][1]benzazepin-11-yl)-N,N,2-trimethylpropan-1-amine
International Nonproprietary Names
INN number INN
1414 trimipramine
Synonyms
7162 RP | IL-6001 | Surmontil®
Database Links
CAS Registry No. 739-71-9
ChEBI CHEBI:9738
ChEMBL Ligand CHEMBL644
DrugBank Ligand DB00726
GtoPdb PubChem SID 178103890
PubChem CID 5584
Search Google for chemical match using the InChIKey ZSCDBOWYZJWBIY-UHFFFAOYSA-N
Search Google for chemicals with the same backbone ZSCDBOWYZJWBIY
Search PubMed clinical trials trimipramine
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Search UniChem for chemical match using the InChIKey ZSCDBOWYZJWBIY-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone ZSCDBOWYZJWBIY
Wikipedia Trimipramine
Comments
Trimipramine is a tricyclic antidepressant (TCA) with antidepressant, anxiolytic, antipsychotic and sedative effects. Trimipramine is a racemic compound of two enantiomers; (S)-trimipramine and (R)-trimipramine. We show the non-stereo structure to represent the mixture.
Marketed formulations may contain trimipramine maleate (PubChem CID 5282318).