vardenafil

Ligand id: 7320

Name: vardenafil

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Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 9
Hydrogen bond donors 2
Rotatable bonds 8
Topological polar surface area 117.18
Molecular weight 489.23
XLogP 2.31
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes (EMA and FDA (2003))
IUPAC Name
2-{2-ethoxy-5-[(4-ethylpiperazin-1-yl)sulfonyl]phenyl}-5-methyl-7-propyl-1H,4H-imidazo[4,3-f][1,2,4]triazin-4-one
International Nonproprietary Names
INN number INN
7950 vardenafil
Synonyms
Levitra®
Database Links
CAS Registry No. 224785-90-4
ChEMBL Ligand CHEMBL1520
DrugBank Ligand DB00862
GtoPdb PubChem SID 178103893
PubChem CID 110634
RCSB PDB Ligand VDN
Search Google for chemical match using the InChIKey SECKRCOLJRRGGV-UHFFFAOYSA-N
Search Google for chemicals with the same backbone SECKRCOLJRRGGV
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Search UniChem for chemical match using the InChIKey SECKRCOLJRRGGV-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone SECKRCOLJRRGGV
SynPHARM 79463 (in complex with phosphodiesterase 5A)
Wikipedia vardenafil
Comments
Vardenafil is a phosphodiesterase type 5 (PDE5A) inhibitor. Marketed formulations may contain vardenafil hydrochloride (PubChem CID 10142962).