thalidomide

Ligand id: 7327

Name: thalidomide

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 1
Rotatable bonds 1
Topological polar surface area 87.04
Molecular weight 258.06
XLogP 1.36
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes (FDA (1998), EMA (2008))
IUPAC Name
2-(6-hydroxy-2-oxo-2,3,4,5-tetrahydropyridin-3-yl)-2,3-dihydro-1H-isoindole-1,3-dione
International Nonproprietary Names
INN number INN
762 thalidomide
Synonyms
K-17
Database Links
CAS Registry No. 50-35-1
ChEMBL Ligand CHEMBL468
DrugBank Ligand DB01041
PubChem CID 5426
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Wikipedia Thalidomide
Comments
Thalidomide is principally an immunomodulatory drug. It inhibits synthesis of TNFα.