tromethamine

Ligand id: 7328

Name: tromethamine

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 4
Rotatable bonds 3
Topological polar surface area 86.71
Molecular weight 121.07
XLogP -2.66
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes (FDA (1965))
IUPAC Name
2-amino-2-(hydroxymethyl)propane-1,3-diol
International Nonproprietary Names
INN number INN
1108 trometamol
Synonyms
tris | trometamol
Database Links
CAS Registry No. 77-86-1 (source: Scifinder)
ChEMBL Ligand CHEMBL1200391
PubChem CID 6503
Search Google for chemical match using the InChIKey LENZDBCJOHFCAS-UHFFFAOYSA-N
Search Google for chemicals with the same backbone LENZDBCJOHFCAS
Search PubMed clinical trials trometamol
Search PubMed titles trometamol
Search PubMed titles/abstracts trometamol
Search UniChem for chemical match using the InChIKey LENZDBCJOHFCAS-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone LENZDBCJOHFCAS
Wikipedia Tris
Comments
Tromethamine (commonly called tris) is used widely as a biochemical buffer, but is also an approved drug (in which case it is sometimes referred to as THAM)..