dexrazoxane

Ligand id: 7330

Name: dexrazoxane

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 8
Hydrogen bond donors 2
Rotatable bonds 3
Topological polar surface area 105.8
Molecular weight 268.12
XLogP -1.3
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes (FDA (1995), EMA (2006))
IUPAC Name
6-hydroxy-4-[(2S)-2-(5-hydroxy-3-oxo-1,2,3,6-tetrahydropyrazin-1-yl)propyl]-2,3,4,5-tetrahydropyrazin-2-one
International Nonproprietary Names
INN number INN
6544 dexrazoxane
Synonyms
ADR-529 | Cardioxane® | ICRF-187 | Zinecard®
Database Links
CAS Registry No. 24584-09-6
ChEMBL Ligand CHEMBL1738
DrugBank Ligand DB00380
GtoPdb PubChem SID 178103902
PubChem CID 71384
Search Google for chemical match using the InChIKey BMKDZUISNHGIBY-ZETCQYMHSA-N
Search Google for chemicals with the same backbone BMKDZUISNHGIBY
Search PubMed clinical trials dexrazoxane
Search PubMed titles dexrazoxane
Search PubMed titles/abstracts dexrazoxane
Search UniChem for chemical match using the InChIKey BMKDZUISNHGIBY-ZETCQYMHSA-N
Search UniChem for chemicals with the same backbone BMKDZUISNHGIBY
Wikipedia Dexrazoxane
Comments
Dexrazoxane is an EDTA derivative with iron-chelating activity.