bazedoxifene

Ligand id: 7355

Name: bazedoxifene

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 2
Hydrogen bond donors 2
Rotatable bonds 7
Topological polar surface area 57.86
Molecular weight 470.26
XLogP 5.92
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes (EMA (2009), FDA (2013))
IUPAC Name
1-[[4-[2-(azepan-1-yl)ethoxy]phenyl]methyl]-2-(4-hydroxyphenyl)-3-methylindol-5-ol
International Nonproprietary Names
INN number INN
8168 bazedoxifene
Synonyms
Conbriza® | TSE-424 | Viviant® | WAY-140424
Database Links
CAS Registry No. 198481-32-2
ChEMBL Ligand CHEMBL46740
GtoPdb PubChem SID 178103927
PubChem CID 154257
RCSB PDB Ligand 29S
Search Google for chemical match using the InChIKey UCJGJABZCDBEDK-UHFFFAOYSA-N
Search Google for chemicals with the same backbone UCJGJABZCDBEDK
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Search UniChem for chemical match using the InChIKey UCJGJABZCDBEDK-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone UCJGJABZCDBEDK
SynPHARM 79264 (in complex with Estrogen receptor-α)
Wikipedia Bazedoxifene
Comments
Bazedoxifene is a selective estrogen receptor modulator (SERM).