cerlapirdine

Ligand id: 7356

Name: cerlapirdine

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 7
Topological polar surface area 83.67
Molecular weight 409.15
XLogP 5.06
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
N,N-dimethyl-3-[(3-naphthalen-1-ylsulfonyl-2H-indazol-5-yl)oxy]propan-1-amine
International Nonproprietary Names
INN number INN
9553 cerlapirdine
Synonyms
PF-05212365 | SAM-531 | WAY-262531
Database Links
CAS Registry No. 925448-93-7 (source: PubChem)
ChEMBL Ligand CHEMBL2103880
PubChem CID 16071605
Search Google for chemical match using the InChIKey NXQGEDVQXVTCDA-UHFFFAOYSA-N
Search Google for chemicals with the same backbone NXQGEDVQXVTCDA
Search PubMed clinical trials cerlapirdine
Search PubMed titles cerlapirdine
Search PubMed titles/abstracts cerlapirdine
Search UniChem for chemical match using the InChIKey NXQGEDVQXVTCDA-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone NXQGEDVQXVTCDA
Wikipedia Cerlapirdine
Comments
Cerlapirdine is a Wyeth/Pfizer selective 5-HT6 receptor antagonist for the treatment of cognitive disorders associated with Alzheimer's disease and schizophrenia [2] . Since the phase 2 trial was stopped development may have ceased. Note, unusually, this INN is PubMed-negative so you will need to search the synonyms to find publications. The hydrochloride salt is CID 53385647.