tasimelteon

Ligand id: 7393

Name: tasimelteon

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 5
Topological polar surface area 38.33
Molecular weight 245.14
XLogP 2.45
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes (FDA (2014), EMA (2015))
IUPAC Name
N-[[(1R,2R)-2-(2,3-dihydro-1-benzofuran-4-yl)cyclopropyl]methyl]propanamide
International Nonproprietary Names
INN number INN
8985 tasimelteon
Synonyms
BMS-214778 | Hetlioz® | VEC-162
Database Links
CAS Registry No. 609799-22-6
ChEMBL Ligand CHEMBL2103822
PubChem CID 10220503
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Search UniChem for chemical match using the InChIKey PTOIAAWZLUQTIO-GXFFZTMASA-N
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Wikipedia Tasimelteon
Comments
Tasimelteon is a melatonin receptor agonist, activating both the MT1 and MT2 receptor subtypes equipotently. Ramelteon and agomelatine are also melatonin receptor agonist class drugs.