avanafil

Ligand id: 7448

Name: avanafil

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Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 9
Hydrogen bond donors 3
Rotatable bonds 10
Topological polar surface area 125.39
Molecular weight 483.18
XLogP 2.01
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes (FDA (2012), EMA (2013))
IUPAC Name
4-[(3-chloro-4-methoxyphenyl)methylamino]-2-[(2S)-2-(hydroxymethyl)pyrrolidin-1-yl]-N-(pyrimidin-2-ylmethyl)pyrimidine-5-carboxamide
International Nonproprietary Names
INN number INN
8572 avanafil
Synonyms
Spedra® | Stendra® | TA-1790
Database Links
CAS Registry No. 330784-47-9
ChEBI CHEBI:66876
ChEMBL Ligand CHEMBL1963681
DrugBank Ligand DB06237
GtoPdb PubChem SID 178104020
PubChem CID 9869929
Search Google for chemical match using the InChIKey WEAJZXNPAWBCOA-INIZCTEOSA-N
Search Google for chemicals with the same backbone WEAJZXNPAWBCOA
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Search UniChem for chemical match using the InChIKey WEAJZXNPAWBCOA-INIZCTEOSA-N
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Wikipedia Avanafil
Comments
Avanafil is a phosphodiesterase type 5 inhibitor.