tafluprost

Ligand id: 7451

Name: tafluprost

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Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 13
Topological polar surface area 75.99
Molecular weight 452.24
XLogP 5.36
No. Lipinski's rules broken 2

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes (FDA (2012))
Is prodrug? Yes
Active form tafluprost acid
IUPAC Name
propan-2-yl (Z)-7-[(1R,2R,3R,5S)-2-[(E)-3,3-difluoro-4-(phenoxy)but-1-enyl]-3,5-dihydroxycyclopentyl]hept-5-enoate
International Nonproprietary Names
INN number INN
8374 tafluprost
Synonyms
AFP-168 | MK-2452 | Taflotan®
Database Links
CAS Registry No. 209860-87-7
ChEBI CHEBI:66899
ChEMBL Ligand CHEMBL1963683
DrugBank Ligand DB08819
PubChem CID 9868491
Search Google for chemical match using the InChIKey WSNODXPBBALQOF-VEJSHDCNSA-N
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Search UniChem for chemical match using the InChIKey WSNODXPBBALQOF-VEJSHDCNSA-N
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Wikipedia Tafluprost
Comments
Tafluprost is a prostaglandin analogue.