peginterferon alfa-2b

Ligand id: 7462

Name: peginterferon alfa-2b

Classification
Compound class Peptide or derivative
Approved drug? Yes (EMA (2000), FDA (2001))
International Nonproprietary Names
INN number INN
7909 peginterferon alfa-2b
Synonyms
PegIntron® | Sylatron®
Database Links
Specialist databases
IMGT/mAb-DB 627
Other databases
ChEMBL Ligand CHEMBL1201561
DrugBank Ligand DB00022
Search PubMed clinical trials peginterferon alfa-2b
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Wikipedia Peginterferon alfa-2b
Comments
Peginterferon alfa-2b is a pegylated interferon protein. Conjugation with polyethylene glycol (PEG) is a strategy commonly used to protect peptide drugs from in vivo proteolytic breakdown to increase their biological half-life and duration of action. It is on the World Health Organization's List of Essential Medicines (link to 2015 list).