pegloticase

Ligand id: 7463

Name: pegloticase

Classification
Compound class Peptide or derivative
Approved drug? Yes (FDA (2010), EMA (2013))
International Nonproprietary Names
INN number INN
8934 pegloticase
Synonyms
Krystexxa® | puricase
Database Links
ChEMBL Ligand CHEMBL1237025
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Wikipedia Pegloticase
Comments
Pegloticase is a porcine-like recombinant uricase, which is PEGylated to increase its biological half-life. The peptide sequence for the enzyme monomer is available in the ChEMBL entry. The enzyme is a tetramer, and lysine residues are PEGylated.