clevidipine

Ligand id: 7468

Name: clevidipine

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 7
Hydrogen bond donors 1
Rotatable bonds 10
Topological polar surface area 90.93
Molecular weight 455.09
XLogP 4.99
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes (FDA (2008))
IUPAC Name
O3-(butanoyloxymethyl) O5-methyl 4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate
International Nonproprietary Names
INN number INN
7490 clevidipine
Synonyms
Cleviprex®
Database Links
CAS Registry No. 167221-71-8
ChEMBL Ligand CHEMBL1237132
DrugBank Ligand DB04920
PubChem CID 153994
Search Google for chemical match using the InChIKey KPBZROQVTHLCDU-UHFFFAOYSA-N
Search Google for chemicals with the same backbone KPBZROQVTHLCDU
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Search UniChem for chemical match using the InChIKey KPBZROQVTHLCDU-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone KPBZROQVTHLCDU
Wikipedia Clevidipine
Comments
Clevidipine is a dihydropyridine class L-type calcium channel blocker, whic is highly selective for vascular smooth muscle over myocardial smooth muscle.