fesoterodine

Ligand id: 7473

Name: fesoterodine

IUPHAR Pharmacology Education Project (PEP) logo

View more information in the IUPHAR Pharmacology Education Project: fesoterodine

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 11
Topological polar surface area 49.77
Molecular weight 411.28
XLogP 7.54
No. Lipinski's rules broken 2

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes (EMA (2007), FDA (2008))
IUPAC Name
[2-[(1R)-3-(di(propan-2-yl)amino)-1-phenylpropyl]-4-(hydroxymethyl)phenyl] 2-methylpropanoate
International Nonproprietary Names
INN number INN
8068 fesoterodine
Synonyms
SPM-8272 | SPM-907 | Toviaz®
Database Links
CAS Registry No. 286930-03-8
ChEMBL Ligand CHEMBL1201764
DrugBank Ligand DB06702
PubChem CID 6918558
Search Google for chemical match using the InChIKey DCCSDBARQIPTGU-HSZRJFAPSA-N
Search Google for chemicals with the same backbone DCCSDBARQIPTGU
Search PubMed clinical trials fesoterodine
Search PubMed titles fesoterodine
Search PubMed titles/abstracts fesoterodine
Search UniChem for chemical match using the InChIKey DCCSDBARQIPTGU-HSZRJFAPSA-N
Search UniChem for chemicals with the same backbone DCCSDBARQIPTGU
Wikipedia Fesoterodine
Comments
The marketed formulation contains the fumarate compound (PubChem CID 9849808). Fesoterodine is an antimuscarinic prodrug, with the active metabolite being 5-hydroxymethyl tolterodine (5-HMT, PubChem CID 9819382).